Do you have any information on what kind of depression was involved? I.e., was it the excess kind (intense sadness) or the deficient kind (feeling flat and numb)? I’m developing a theory that hops is contraindicated for the second kind but not necessarily the first.

Yes, morning insomnia is often associated with depression — and I don’t give hops for morning insomnia, I tend to use it for people who have trouble falling asleep due to agitation.

You can also divide crowns and share the rhizomes - or sell, if you know the variety - your Hops plants with Home-Brewers.
A Hops shortage will greatly raise prices the next couple of years…so these pleasant vines are valuable to some of us.

Store Hops flowers in a Freezer Bag after harvest - best used for brewing fairly Fresh…before the next season’s harvest.

I think there’s plenty of hope for grandma!

I would suggest looking up an herbalist in your area for a personal consultation — there are so many things that can affect sleep that I don’t think you’re likely to get much useful advice online.

I would ask around about local herbalists, or look online. (The American Herbalists Guild is one resource, though they only list herbalists who are professional members of their organization.)